1 “... reduction or relapse prevention. We conducted an a priori search for primary trial evidence related...”

2 “... reduction or relapse prevention. We conducted an a priori search for primary trial evidence related...”

3

4

5 “... trials were conducted only in women, and the fifth trial was primarily among older adult women (84%)....”

6 “... trials were conducted only in women, and the fifth trial was primarily among older adult women (84%)....”

7 “..., with statistical tests of strata differences conducted. Funnel plots and tests for small-study effects were...”

8 “..., with statistical tests of strata differences conducted. Funnel plots and tests for small-study effects were...”

9 “... of screening in pregnancy, and KQ3) harms of penicillin in pregnancy. DATA SOURCES: We conducted a literature...”

10 “... of screening in pregnancy, and KQ3) harms of penicillin in pregnancy. DATA SOURCES: We conducted a literature...”

11 “... for this topic. DATA SOURCES: We conducted a literature search of PubMed and the Cochrane Central Register...”

12 “... for this topic. DATA SOURCES: We conducted a literature search of PubMed and the Cochrane Central Register...”

13 “... outcomes, but evidence of effectiveness remains primarily derived from trials conducted in treatment...”

14 “... outcomes, but evidence of effectiveness remains primarily derived from trials conducted in treatment...”

15

16

17

18

19 “...OBJECTIVE: We conducted this systematic review to support the U.S. Preventive Services Task Force...”

20 “.... Other trials, not conducted in the US, evaluating more intensive self-management interventions...”