1 “..., is important both for safety reasons and to ensure optimal treatment response...”

2 “..., is important both for safety reasons and to ensure optimal treatment response...”

3 “... adolescents in primary care or school settings report sensitivity of 73 to 100 percent and specificity of 65...”

4 “... adolescents in primary care or school settings report sensitivity of 73 to 100 percent and specificity of 65...”

5 “... in young children did not target drug use specifically and typically reported behavioral and academic...”

6 “... in young children did not target drug use specifically and typically reported behavioral and academic...”

7

8

9

10

11

12

13 “... trials reported in 57 publications; 16 (n=56,110) were newly published trials that were not included...”

14 “... pulmonary function in adults in addition to reducing asthma symptoms, but medication use was rarely reported...”

15 “... pulmonary function in adults in addition to reducing asthma symptoms, but medication use was rarely reported...”

16 “... trials reported in 57 publications; 16 (n=56,110) were newly published trials that were not included...”

17 “... were relatively small and highly variable. The clinical significance of the small benefit of medication...”

18 “... were relatively small and highly variable. The clinical significance of the small benefit of medication...”

19

20 “..., only the GAD-2 and GAD-7 were reported by more than one study and demonstrated adequate accuracy...”