1 “... commercial information. Academic partners face significant cultural barriers to sharing data...”

2 “... to significant differences in the pharmacokinetics (PK)2 and pharmacodynamics (PD)3 of a given drug compared...”

3 “...Cancer treatment can lead to an array of significant short- and long-term physical, psychosocial...”

4 “... in the number of patients diagnosed with cancer. Significant advances in cancer research, screening...”

5 “..."In recent years, significant progress has been made in the clinical development and use of various...”

6 “... to cause not only significant acute side effects, but also lead to numerous long-term health risks...”

7 “... significant challenges to developing, validating, and effectively implementing new cancer screening approaches...”