1 “... for more than 50 years. Formerly known as the NCI Clinical Trials Cooperative Group Program, the NCTN...”

2 “..."Despite spending more time and money in developing novel therapeutics, the success rate for new...”

3 Table of Contents: “... and implementation -- Increasing diversity -- Developing more pragmatic and patient-centered trials -- Wrap-up...”

4 “... and improve health outcomes across the continuum of cancer care. However, estimates suggest that more than one...”

5 “... and improve health outcomes across the continuum of cancer care. However, estimates suggest that more than one...”

6 “... have become more complex, with multisite trials now common, and there is increasing use of archived...”

7 “...Rapid advances in cancer research, the development of new and more sophisticated approaches...”

8

9 “... and reaching eligible populations, addressing health disparities, and many more considerations. In recognition...”

10 “... as that of the tumor --and to allow for more rapid learning from patient experiences. To further examine informatics...”

11 “.... However, as the field continues to develop and advance, cancer care has become more complex than ever...”

12 “... participants suggested many potential actions to provide patient-centered cancer care, to foster more...”

13 “... at an earlier and more curable stage. But the ability of such screening to accurately detect early cancers...”

14 “... research, increasing health care access and quality, and making care more personalized. It encompasses...”

15 “... optimal screening intervals, the ages at which screening should begin and end, as well as more specific...”

16

17 “..., approximately 8 times more than children under age 15. This population faces a variety of unique short- and long...”

18

19 “... infrastructure and care costs. As a result, worse outcomes for patients with cancer are more common in low...”