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9 “... number of new studies, the overall high risk of bias of many of these studies necessitated ratings of low...”

10 “... number of new studies, the overall high risk of bias of many of these studies necessitated ratings of low...”

11 “... popular due to their flexibility and interpretability. Many randomized clinical trials report multiple...”

12 “... popular due to their flexibility and interpretability. Many randomized clinical trials report multiple...”

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15 “... that could be used to determine if, and how many, models exist on a particular disease of interest....”

16 “... that could be used to determine if, and how many, models exist on a particular disease of interest....”

17 “...More RCTs and better designed observational studies that can control for many of the known...”

18 “...More RCTs and better designed observational studies that can control for many of the known...”

19 “... more than offset by findings of no effect for other outcomes. Many interventions (e.g., nutraceuticals...”

20 “... more than offset by findings of no effect for other outcomes. Many interventions (e.g., nutraceuticals...”