1 Subjects: “...Randomized Controlled Trials as Topic...”

2 Subjects: “...Randomized Controlled Trials as Topic...”

3 “...While three poor-quality analytic validity studies showed that technological advances can improve...”

4 “... confounders, and use of study designs complicated by recall bias. Results from the observational literature...”

5 “... across a range of patient outcomes. One of the two trials (n=114) evaluating the same exercise-focused...”

6 “... no studies designed to assess the adverse effects of dietary counseling and none of the included healthful...”

7 “... no studies designed to assess the adverse effects of dietary counseling and none of the included healthful...”

8 “... on the availability of intensive counseling in practice and real-world fidelity and adherence to these interventions...”

9 “... on the availability of intensive counseling in practice and real-world fidelity and adherence to these interventions...”

10 “...Two trials reported conflicting results on total or fatal hemorrhagic CVA risk with wide confidence...”

11 “...Two trials reported conflicting results on total or fatal hemorrhagic CVA risk with wide confidence...”

12 “... found no trial evidence that examined the effect of screening for cognitive impairment on patient...”

13 “... found no trial evidence that examined the effect of screening for cognitive impairment on patient...”

14

15

16 “.... NRI). These differences make comparisons between risk prediction studies difficult, which limited our...”

17 “.... NRI). These differences make comparisons between risk prediction studies difficult, which limited our...”

18 “...? DATA SOURCES: We searched MEDLINE, PubMed, and the Cochrane Central Register of Controlled Trials...”

19 “... trials comparing traditional cardiovascular risk assessment to risk assessment using nontraditional risk...”

20 “... trials comparing traditional cardiovascular risk assessment to risk assessment using nontraditional risk...”