1

2 “... and continuous outcomes. For objective 2, we conducted two types of meta-regression. One explored subgroup...”

3

4 “... and continuous outcomes. For objective 2, we conducted two types of meta-regression. One explored subgroup...”

5

6 “... the effectiveness of isoniazid for preventing active TB was published more than 40 years ago and was conducted among...”

7 “... data from, and rated risk of bias of relevant studies. We conducted meta-analyses or network meta...”

8 “... data from, and rated risk of bias of relevant studies. We conducted meta-analyses or network meta...”

9

10

11

12

13

14

15