1 Subjects: “...United States...”

2 “...Eligible studies included randomized controlled trials (RCTs), nonrandomized trials...”

3

4 “... SOURCES: PubMed/MEDLINE, the Cochrane Library, EMBASE, and trial registries through March 31, 2016...”

5 “... SOURCES: PubMed/MEDLINE, the Cochrane Library, EMBASE, and trial registries through March 31, 2016...”

6

7 “...Trials showing clinically meaningful benefit in hearing-related function among groups receiving...”

8 Subjects: “...United States...”

9

10

11

12 “... in the United States. DATA SOURCES: PubMed/MEDLINE, the Cochrane Library, Embase, and trial registries through...”

13 “... that showed efficacy. DATA SOURCES: MEDLINE(r), Cochrane Library, CINAHL(r), ClinicalTrials.gov, and World...”

14 “... that showed efficacy. DATA SOURCES: MEDLINE(r), Cochrane Library, CINAHL(r), ClinicalTrials.gov, and World...”