1 “... assessment, grading the strength of the evidence, and data synthesis were all carried out according...”

2 “... assessment, grading the strength of the evidence, and data synthesis were all carried out according...”

3

4

5 “... between long-acting opioids. The 2 trials which found a significant difference were both open-label, rated...”

6 “... between long-acting opioids. The 2 trials which found a significant difference were both open-label, rated...”

7 “.... Misuse and diversion rates varied by age and were highest among college students, and rates of diversion...”

8 “... the strength of the evidence, and data synthesis were all carried out according to standard Drug Effectiveness...”

9 “... the strength of the evidence, and data synthesis were all carried out according to standard Drug Effectiveness...”

10

11

12 “... assessment, grading the strength of the evidence, and data synthesis were all carried out according...”

13 “... assessment, grading the strength of the evidence, and data synthesis were all carried out according...”

14

15

16 “... of the evidence, and data synthesis were all carried out according to our standard review methods. RESULTS...”

17 “... of the evidence, and data synthesis were all carried out according to our standard review methods. RESULTS...”

18 “... antihistamines were developed to decrease the adverse effects of first generation drug. "Second generation...”

19 “... antihistamines were developed to decrease the adverse effects of first generation drug. "Second generation...”

20 “... antihistamines were developed to decrease the adverse effects of first generation drug. "Second generation...”