1 Subjects: “...Cohort Studies...”

2 Subjects: “...Cohort Studies...”

3 “...-to-head cohort studies and placebo-controlled trials. For oral DMARDs, including sulfasalazine...”

4 “...-to-head cohort studies and placebo-controlled trials. For oral DMARDs, including sulfasalazine...”

5 “... was similar, and (4) studies were double-blinded randomized controlled trials of low or medium risk of bias...”

6 “... was similar, and (4) studies were double-blinded randomized controlled trials of low or medium risk of bias...”