1 Subjects: “...Data Collection...”

2 Subjects: “...Data Interpretation, Statistical...”

3 “...CONCLUSIONS: The results suggest that contacting authors to obtain additional data will likely...”

4 “...DATA EXTRACTION: One investigator abstracted data and a second investigator checked data...”

5

6

7 “... and on the association between intermediate outcomes following antiviral therapy and clinical outcomes. DATA EXTRACTION...”

8

9

10 “...Antiviral treatment can successfully eradicate viremia, but data on long-term clinical outcomes...”

11 “...Antiviral treatment can successfully eradicate viremia, but data on long-term clinical outcomes...”

12

13

14 “... of cardiovascular complications appear low. There are insufficient data to estimate the effects of counseling...”

15 “... data from randomized trials, greater reductions in low-density lipoprotein cholesterol levels...”

16 “... data from randomized trials, greater reductions in low-density lipoprotein cholesterol levels...”

17 “... of cardiovascular complications appear low. There are insufficient data to estimate the effects of counseling...”

18 “... adverse events. There are insufficient data to estimate the effects of interventions during pregnancy...”

19 “... adverse events. There are insufficient data to estimate the effects of interventions during pregnancy...”

20 “... observational studies that reported clinical outcomes associated with use of amplification. DATA EXTRACTION: One...”