1

2

3 “... if there are clinically significant differences between dual therapy with pegylated interferon-alfa 2a versus pegylated...”

4 “... difference [WMD] 7.55 on a 0 to 100 scale, 95% CI 11.4 to 3.74) (strength of evidence [SOE]: moderate), mean...”

5 “... difference [WMD] 7.55 on a 0 to 100 scale, 95% CI 11.4 to 3.74) (strength of evidence [SOE]: moderate), mean...”

6 “... if there are clinically significant differences between dual therapy with pegylated interferon-alfa 2a versus pegylated...”

7 “...There were no clear differences between glucosamine or chondroitin and oral NSAIDs for pain...”

8 “...There were no clear differences between glucosamine or chondroitin and oral NSAIDs for pain...”

9

10

11

12

13

14 “...4.9%, RR, 1.47, 95% CI 1.19 to 1.80); other serious harms were infrequent, with no differences...”

15

16

17

18

19 “... higher risk of withdrawal due to adverse events than placebo, but there was no difference in risk...”

20 “... higher risk of withdrawal due to adverse events than placebo, but there was no difference in risk...”