1 “... biological mesh, absorbable synthetic mesh, and non-absorbable synthetic mesh. Biological meshes...”

2 “... biological mesh, absorbable synthetic mesh, and non-absorbable synthetic mesh. Biological meshes...”

3 Subjects: “...Biological Products / therapeutic use...”

4 “... and safety, as well as evidence-based clinical guidelines, on the practice of switching biologics, both...”

5 Subjects: “...Biological Products / therapeutic use...”

6 “... of biologics and immunomodulators among UC patients naïve to both types of drugs...”

7 “...Up to one-third of inflammatory bowel disease (IBD) patients can experience that biologics become...”

8 “... and Submission Guidelines for Subsequent Entry Biologics (March, 2014). The CDR team reviewed the information...”

9 Subjects: “...Biological Products / therapeutic use...”

10 “... and Submission Guidelines for Subsequent Entry Biologics (March, 2014). The CDR team reviewed the information...”

11 Subjects: “...Biological Products / therapeutic use...”

12 Subjects: “...Biological Products / therapeutic use...”

13 Subjects: “...Biological Assay / methods...”

14 Subjects: “...Biological Assay / methods...”

15 “...Given the theorized benefits of a top-down approach (early use of biologics), there is growing...”

16 “...Given the theorized benefits of a top-down approach (early use of biologics), there is growing...”

17 “... of the TST for patients with compromised immunity prior to initiating biologic treatment. Additionally...”

18

19 “... with immunomodulators or corticosteroids -- but never failed treatment with a biologic -- or have failed or were...”

20 “...Chronic pain serves no biological purpose in contrast with acute pain, which warns of disease...”