The complosome as orchestrator of normal cell physiology
Liver-derived and serum-circulating complement is undeniably quintessential for innate immunity by detecting and eliminating infectious microorganisms. However, unexpectedly, cell-autonomous complement expression and its intracellular activities emerged recently as fundamental driver of normal cell...
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Format: | eBook |
Language: | English |
Published: |
London
Henry Stewart Talks
2024, 2024
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Series: | The biomedical & life sciences collection
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Subjects: | |
Online Access: | |
Collection: | Henry Stewart Talks - Collection details see MPG.ReNa |
Summary: | Liver-derived and serum-circulating complement is undeniably quintessential for innate immunity by detecting and eliminating infectious microorganisms. However, unexpectedly, cell-autonomous complement expression and its intracellular activities emerged recently as fundamental driver of normal cell metabolism and physiology. In consequence, perturbations in intracellular complement - coined the complosome - are associated with a range of human diseases. Understanding these emerging novel and non-canonical roles of the complosome will help creating new platforms for needed therapeutic interventions. |
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Item Description: | Title from title frames. - Webinar. - Mode of access: World Wide Web |
Physical Description: | 1 streaming video file (67 min.) color, sound |