The complosome as orchestrator of normal cell physiology

Liver-derived and serum-circulating complement is undeniably quintessential for innate immunity by detecting and eliminating infectious microorganisms. However, unexpectedly, cell-autonomous complement expression and its intracellular activities emerged recently as fundamental driver of normal cell...

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Bibliographic Details
Main Author: Kemper, Claudia
Format: eBook
Language:English
Published: London Henry Stewart Talks 2024, 2024
Series:The biomedical & life sciences collection
Subjects:
Online Access:
Collection: Henry Stewart Talks - Collection details see MPG.ReNa
Description
Summary:Liver-derived and serum-circulating complement is undeniably quintessential for innate immunity by detecting and eliminating infectious microorganisms. However, unexpectedly, cell-autonomous complement expression and its intracellular activities emerged recently as fundamental driver of normal cell metabolism and physiology. In consequence, perturbations in intracellular complement - coined the complosome - are associated with a range of human diseases. Understanding these emerging novel and non-canonical roles of the complosome will help creating new platforms for needed therapeutic interventions.
Item Description:Title from title frames. - Webinar. - Mode of access: World Wide Web
Physical Description:1 streaming video file (67 min.) color, sound