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Down Syndrome Neuropsychological Phenotype across the Lifespan

Down syndrome (DS), caused by the triplication of chromosome 21, is the most common genetic cause of intellectual disability (ID). Individuals with DS commonly exhibit unique neuropsychological profiles that emerge during specific developmental stages across the lifespan, often characterized by earl...

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Bibliographic Details
Main Author: Pulsifer, Margaret B.
Format: eBook
Language:English
Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
Subjects:
Apoe Ɛ4
Early-onset Alzheimer Disease
Idiopathic Regression
Depression
Cognition
Co-occurring
Screening
Dementia
N/a
Mild Cognitive Impairment
Cognitive Decline
Social Cognition
Measurement
Letters
Free T4
Selective Serotonin Reuptake Inhibitor
Independence
Trisomy 21
Audiovisual Processing
Comorbidity
Prevalence
Down Syndrome
Phonological Awareness
Primary Care
Vocabulary
Early Regression
Fluency
Autism Spectrum Disorder
Children
Functional Independence
Co-occurrence
Neuropsychological Assessment
Proxy-report
Late-onset Alzheimer Disease
Biomarkers
Language
Regression
Cognitive Function
Disfluency
Tsh
Social Behavior
Communicative Abilities In Infants
Neurosciences / Bicssc
Alzheimer's Disease
Thyroid Autoantibodies
Hypothyroidism
Transition To Adulthood
Medicine And Nursing / Bicssc
Decoding
Neuropsychological Tests
Attention
Online Access:
Collection: Directory of Open Access Books - Collection details see MPG.ReNa
Description
Summary:Down syndrome (DS), caused by the triplication of chromosome 21, is the most common genetic cause of intellectual disability (ID). Individuals with DS commonly exhibit unique neuropsychological profiles that emerge during specific developmental stages across the lifespan, often characterized by early developmental delay, cognitive strengths and weaknesses, behavior and mental health issues, and age-related cognitive decline, frequently resulting in early-onset Alzheimer's disease. These profiles are unique compared to other individuals with ID and reflect the genetic mechanisms and neuroanatomic features underlying the distinct neuropsychological phenotype associated with DS. This Special Issue aims to highlight the recent advancements in understanding the neuropsychological phenotype associated with DS across the lifespan. The lifespan perspective will cover four developmental stages: (1) early childhood; (2) school age; (3) young adulthood, and (4) older adulthood. Authors contributed cutting-edge original research studies and comprehensive reviews that address a broad range of topics related to DS, including early developmental trajectories, cognitive functioning, language, adaptive skills, behavior and mental health, assessment and diagnosis, age-related cognitive decline, and medical issues related to the neuropsychological phenotype and neuroimaging.
Item Description:Creative Commons (cc), https://creativecommons.org/licenses/by/4.0/
Physical Description:1 electronic resource (180 p.)
ISBN:books978-3-0365-3961-4
9783036539614
9783036539621

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