Review of the Department of Defense biokinetic modeling approach in support of establishing an airborne lead exposure limit

Biokinetic modeling provides a mathematical technique for estimating absorption, distribution, metabolism, and excretion of chemicals, including particles and metals, in humans. Such models can be used to relate the amount of lead external exposure to the amount of lead found in the blood and other...

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Bibliographic Details
Corporate Authors: National Academies of Sciences, Engineering, and Medicine (U.S.) Committee to Review DoD's Proposed Occupational Exposure Limits for Lead, United States Department of Defense
Format: eBook
Language:English
Published: Washington, DC National Academies Press [2020], 2020
Series:Consensus study report of the National Academies of Sciences, Engineering, Medicine
Subjects:
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
Description
Summary:Biokinetic modeling provides a mathematical technique for estimating absorption, distribution, metabolism, and excretion of chemicals, including particles and metals, in humans. Such models can be used to relate the amount of lead external exposure to the amount of lead found in the blood and other tissues at different points in time. At the request of the Department of Defense (DoD), Review of the Department of Defense Biokinetic Modeling Approach in Support of Establishing an Airborne Lead Exposure Limit evaluates whether the model used by DoD to derive airborne lead concentrations from blood lead levels is appropriate. This report also considers whether DoD's modifications to the model are appropriately justified, and whether the assumptions in and inputs to the model are reasonable
Physical Description:1 PDF file (xi, 36 pages) illustrations
ISBN:0309671922
9780309671927