Genetics of Male Infertility A Case-Based Guide for Clinicians
This unique, case-based guide provides a thoughtful and comprehensive overview of the genetic basis of male infertility for the practicing clinician. In addition to discussing the molecular foundations of sperm production and the consequences of genetic abnormalities on various stages of sperm devel...
| Other Authors: | , , , |
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| Format: | eBook |
| Language: | English |
| Published: |
Cham
Springer International Publishing
2020, 2020
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| Edition: | 1st ed. 2020 |
| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Part I: The Genetic Basis of Reproduction
- The Molecular Genetics of Testis Determination
- Molecular Regulation of Sperm Production Cascade
- Spermatozoal Chromatin Structure: Role in Sperm Functions and Fertilization
- Genetic Basis of Endocrine Regulation of Spermatogenesis
- Epidemiology of Genetic Disorders in Male Infertility
- Genetic Evaluation of Male Infertility
- Part II: Impact of Genetics on the Sperm Cell
- Genetic Basis of Sperm Morphologic Defects: Head Defects, Body and Tail Defects
- Mitochondrial Function and Male Infertility
- Sperm DNA Fragmentation and Male Infertility
- The Sperm Epigenome and Potential Implications for the Developing Embryo
- Part III: Clinical Case Scenarios
- Klinefelter Syndrome
- Chromosomal Translocations and Inversion in Male Infertility
- Genetics of Vas Aplasia
- Anomalies of the Y Chromosome
- Infertility and Cryptorchidism
- Kartagener and Immotile CiliaSyndrome
- Persistent Müllerian Duct Syndrome
- Disorders of Sex Determination
- Endocrine Genetic Defects
- Sperm Aneuploidy
- Part IV: Genetic Infertility: Is There Any Hope?- Sperm DNA Fragmentation
- The Potential of CRISPR/Cas Gene Editing to Correct Male Infertility