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200301 r ||| eng |
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|a Thompson, Wade
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|a Early biologic treatment versus conventional treatment for the management of Crohn's disease
|h Elektronische Ressource
|b a review of comparative clinical effectiveness and cost-effectiveness
|c Wade Thompson, Charlene Argáez
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|a Version 1.0
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|a Ottawa
|b CADTH
|c February 13, 2019, 2019
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|a 1 PDF file (47 pages)
|b illustrations
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|a Includes bibliographical references
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|a Comparative Effectiveness Research
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|a Canada
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|a Cost-Benefit Analysis
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|a Tumor Necrosis Factor Inhibitors / economics
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|a Adrenal Cortex Hormones / economics
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|a Early Medical Intervention
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|a Tumor Necrosis Factor Inhibitors / therapeutic use
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|a Treatment Outcome
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|a Adrenal Cortex Hormones / therapeutic use
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|a Crohn Disease / drug therapy
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|a Immunomodulation
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|a Argáez, Charlene
|e [author]
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|a Canadian Agency for Drugs and Technologies in Health
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|a Canadian Agency for Drugs and Technologies in Health
|b Rapid Response Service
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|a eng
|2 ISO 639-2
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|b NCBI
|a National Center for Biotechnology Information
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|a CADTH rapid response report: peer-reviewed summary with critical appraisal
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|u https://www.ncbi.nlm.nih.gov/books/NBK543466
|3 Volltext
|n NLM Bookshelf Books
|3 Volltext
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|a 610
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|a 330
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|a Given the theorized benefits of a top-down approach (early use of biologics), there is growing interest in its clinical effectiveness, safety, and cost-effectiveness compared to a conventional treatment approach, both in children and adults. As such, this report sought to summarize the evidence regarding the clinical and cost-effectiveness of early biologic therapy compared to conventional treatment for Crohn's disease in children and adults. This is an upgrade of a previous CADTH rapid response titled "Early Treatment versus Conventional Treatment for the Management of Luminal Crohn's Disease: A Review of Comparative Clinical Effectiveness and Cost-Effectiveness"
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