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| 008 |
140122 ||| eng |
| 020 |
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|a 9789400991040
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| 100 |
1 |
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|a Pullman, A.
|e [editor]
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| 245 |
0 |
0 |
|a Carcinogenesis: Fundamental Mechanisms and Environmental Effects
|h Elektronische Ressource
|b Proceedings of the Thirteenth Jerusalem Symposium on Quantum Chemistry and Biochemistry Held in Jerusalem, Israel, April 28 – May 2, 1980
|c edited by A. Pullman, Paul O.P. Ts'O, H. Gelboin
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| 250 |
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|a 1st ed. 1980
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| 260 |
|
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|a Dordrecht
|b Springer Netherlands
|c 1980, 1980
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| 300 |
|
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|a IX, 592 p
|b online resource
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| 505 |
0 |
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|a Stereochemical Aspects of Benzo (a) pyrene Metabolism and Biochemical Individuality in Human Cells -- Metabolic and Structural Requirements for the Carcinogenic Potencies of Unsubstituted and Methyl-Substituted Polycyclic Aromatic Hydrocarbons -- Formation and Inactivation of DNA-Binding Metabolites of Benzo (a) pyrene Studied with Isolated Cells and Subcellular Fractions -- Enzymic Control of Reactive Metabolites from Aromatic Carcinogens -- Aflatoxin-DNA Interactions: Qualitative, Quantitative and Kinetic Features in Relation to Carcinogenesis -- Structural Modifications and Specific Recognition by Antibodies of Carcinogenic Aromatic Amines Bound to DNA -- Immunological Detection and Quantification of DNA Components Structurally Modified by Alkylating Carcinogens (Ethylnitrosourea). -- Characteristics of Stages of Hepatocarcinogenesis -- Mechanisms ofGenetic Susceptibility to Cancer --
|
| 505 |
0 |
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|a Monoclonal Antibodies in the Study of Human Cancer -- Oculo-Cutaneous and Internal Neoplasmas in Xeroderma Pigmentosum: Implications for Theories of Carcinogenesis -- The Induction, Expression and Modulation of Radiation Induced Oncogenesis In Vitro in Diploid Humand and Rodent Cells -- Progress in Cloning the Transforming Gene from Chemically- Transformed Mouse Cells -- Relationship Between Transformation and Mutation in Mammalian Cells -- Membrane and Other Biochemical Effects of the Phorbol Esters and Their Relevance to Tumor Promotion -- The Chemistry of Poly- cyclic Aromatic Hydrocarbon-DNA Adducts -- Index of Subjects
|
| 505 |
0 |
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|a Constitutive Uncoupling of Pathways of Gene Expression that Control Growth and Differentiation and the Molecular Mechanism of Carcinogenesis -- Amplification of Carcinogenesis by Non-Carcinogens - Diterpene Type Promoters and Models of Environmental Exposure -- Reduction of Human Exposure to Environmental N-Nitrosocarcinogens. Examples of Possibilities for Cancer Prevention -- Endogenous Carcinogenesis: Nitrate, Nitrite and N-Nitroso Compounds -- Neoplastic Transformation, Somatic Mutation, and Differentiation -- Oncogenic Transformation, Initiation, Promotion and Mutagenesis in C3H/10T1/2 Cells -- Dissection of the Early Molecular Events in the Activation of Lymphocytes by 12-0- Tetradecanoylphorbol-13-acetate -- Modulation of Adipose Conversion of BALB/c 3T3 Cells by Tumor Promotors -- Established Cell Cultures as Model Systems for Carcinogen Metabolism -- Regulation of the Expression of SV40 T Antigen in Stem Versus Differentiated Cells --
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| 505 |
0 |
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|a Carcinogenicity of Polycyclic Aromatic Hydrocarbons: The Bay-Region Theory -- Inactivation of ØX174 and SV 40 Viral DNA Replication by Diol Epoxide Derivatives of Carcinogenic Polycyclic Hydro-carbons -- Dihydrodiols and Diol-Epoxides in the Activation and Detoxification of Polycyclic Hydrocarbons -- Metabolically Generated Free Radicals from Many Types of Chemical Carcinogens and Binding of the Radicals with Nucleic Acid Bases -- Nucleophilicity of DNA. Relation to Chemical Carcinogenesis -- An Analysis of the Reactivities of Epoxide Rings in Some Cyclic Hydrocarbons -- Biological Effects of Specific Hydrocarbon-DNA Reactions -- The Effect of Base Modification on Fidelity in Transcription -- Modification of DNA by Carcinogenic Aromatic Amines In Vivo and In Vitro with Possible Promutagenic Consequences -- Bio-chemical Considerations of the Enzymology Associated with Quinone and Tetrol Formation During Benzo (a) pyrene Metabolism --
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| 505 |
0 |
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|a The Effect of 12-0- Tetradecanoyl-phorbol-13-acetate (TPA) on Cell Transformation by Simian Virus 40 Mutants -- The Use of Cell Cultures to Assay the Effects of Chemicals on Bone Marrow -- Structural Modifications and Their Effects on the Genetic Functions of DNA Generated by Interactions with Benro (a) pyrene Metabolites -- Neoplastic Transformation of Human Mutant Cells by a Tumor Promoter -- Use of Human Epidermal Keratinocytes in Studies on Chemical Carcinogenesis -- Studies on Why 12-0-Tetra- decanoyl-phorbol-13-acetate (TPA) Does Not Promote Epidermal Carcinogenesis of Hamsters -- Modulation of Repair of DNA Damages Induced by Nitrosamines -- DNA Repair in Human Cells Exposed to Combinations of Carcinogenic Agents -- Reactions of Aflatoxin B1, Damaged DNA In Vitro and In Situ in Mammalian cells -- The Role ofDNA Repair in Preventing the Cytotoxic and Mutagenic Effects of Carcinogens in Human Cells -- Transformation of Diploid Human Fibroblasts by Chemical Carcinogens --
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| 653 |
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|a Physical chemistry
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| 653 |
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|a Physical Chemistry
|
| 700 |
1 |
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|a Ts'O, Paul O.P.
|e [editor]
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| 700 |
1 |
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|a Gelboin, H.
|e [editor]
|
| 041 |
0 |
7 |
|a eng
|2 ISO 639-2
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| 989 |
|
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|b SBA
|a Springer Book Archives -2004
|
| 490 |
0 |
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|a Jerusalem Symposia
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| 028 |
5 |
0 |
|a 10.1007/978-94-009-9104-0
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| 856 |
4 |
0 |
|u https://doi.org/10.1007/978-94-009-9104-0?nosfx=y
|x Verlag
|3 Volltext
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| 082 |
0 |
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|a 541
|