Purinergic Receptors and their Modulators
This book overviews purinergic receptors that are playing key roles in human and pathophysiological processes. The book elaborates on how selective P1 and P2 modulators have been developed as therapeutics for a variety of diseases. It also provides an overview of current perspectives in the design o...
| Other Authors: | , |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
Cham
Springer International Publishing
2023, 2023
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| Edition: | 1st ed. 2023 |
| Series: | Topics in Medicinal Chemistry
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| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Once upon a time adenosine and its receptors. Historical survey and perspectives as potential targets for therapy in human diseases
- Adenosine receptor ligands, probes and functional conjugates: A twenty-year history of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines (PTP)
- Adenosine receptor ligands as potential therapeutic agents for impaired wound healing and fibrosis
- Adenosine A2A receptor antagonists: chemistry, SARs, modeling studies and therapeutic potential
- A2B Adenosine Receptor as a new and attractive target to treat brain ischemia or demyelination
- A3 adenosine receptor ligands: from discovery to clinical trials
- Bifunctional tools to study adenosine receptors
- Allosteric modulators of adenosine receptors
- New computational approaches in inspecting adenosine receptor-ligand recognition process
- P2X4 receptors in immunity and inflammation
- CD73 inhibitors as antitumor agents
- Bacterial ectonucleotidases- underexplored antibacterial targets.