Synthetic gene network modeling, analysis, and robust design methods

This book develops a rational design and systematic approach to construct a gene network with desired behaviors. In order to achieve this goal, the registry of standard biological parts and experimental techniques are introduced at first. Then these biological components are characterized by a stand...

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Bibliographic Details
Main Authors: Chen, Bor-Sen, Wang, Yu-Chao (Author)
Format: eBook
Language:English
Published: Boca Raton CRC Press/Taylor & Francis Group 2014
Subjects:
Online Access:
Collection: O'Reilly - Collection details see MPG.ReNa
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245 0 0 |a Synthetic gene network  |b modeling, analysis, and robust design methods  |c Bor-Sen Chen and Yu-Chao Wang 
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300 |a vi, 208 pages  |b illustrations 
505 0 |a Includes bibliographical references and index 
505 0 |a Mathematical models and design specifications in synthetic gene networks -- Robust synthetic biology designs based on system dynamic models -- Robust synthetic biology designs based on network evolutionary methods -- Construction of promoter and promoter-RBS libraries for synthesis of gene networks -- Robust synthetic gene network designs based on library-search method -- Robust design of synthetic biological filter and transistor based on promoter-RBS libraries -- Communication and synchronization of a population of coupled synthetic gene networks 
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653 |a Genetic Engineering 
653 |a Genes, Synthetic 
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520 |a This book develops a rational design and systematic approach to construct a gene network with desired behaviors. In order to achieve this goal, the registry of standard biological parts and experimental techniques are introduced at first. Then these biological components are characterized by a standard modeling method and collected in the component libraries, which can be efficiently reused in engineering synthetic gene networks. Based on the system theory, some design specifications are provided to engineer the synthetic gene networks to robustly track the desired trajectory by employing the component libraries