Chronic inflammation, immune cell trafficking and anti-trafficking agents

Inflammatory bowel diseases (IBDs) are characterized by uncontrolled activation of intestinal immune cells in a genetically susceptible host (reviewed in Nat Immunol. 2019 Aug;20(8):970-979). Studies have identified altered trafficking of immune cells and pathogenic immune cell circuits as crucial p...

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Bibliographic Details
Main Author: Jefremow, André
Format: eBook
Language:English
Published: London Henry Stewart Talks 2023, 2023
Series:The biomedical & life sciences collection
Subjects:
Online Access:
Collection: Henry Stewart Talks - Collection details see MPG.ReNa
Description
Summary:Inflammatory bowel diseases (IBDs) are characterized by uncontrolled activation of intestinal immune cells in a genetically susceptible host (reviewed in Nat Immunol. 2019 Aug;20(8):970-979). Studies have identified altered trafficking of immune cells and pathogenic immune cell circuits as crucial pathways for mucosal inflammation and tissue destruction in IBD. Two major factors, namely a defective gut barrier and microbial dysbiosis, favour mucosal inflammation and lead to accumulation and local activation of immune cells.
Item Description:Title from title frames. - Webinar. - Mode of access: World Wide Web
Physical Description:1 streaming video file (57 min.) color, sound