A phase II, multicenter, randomized, double-blind, placebo-controlled, parallel group study to determine the pharmacodynamics of sodium nitroprusside during prolonged infusion in pediatric subjects
A Phase II, randomized, double-blind, withdrawal to placebo study examining the efficacy, safety, and tolerability of sodium nitroprusside (SNP) in pediatric subjects. Objectives were to determine the persistence of the effect of SNP on blood pressure during stable infusion regimens lasting at least...
| Main Authors: | , |
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| Corporate Authors: | , |
| Format: | eBook |
| Language: | English |
| Published: |
Bethesda, MD
Eunice Kennedy Shriver National Institute of Child Health and Human Development
February 1, 2012, 2012
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| Online Access: | |
| Collection: | National Center for Biotechnology Information - Collection details see MPG.ReNa |
| Summary: | A Phase II, randomized, double-blind, withdrawal to placebo study examining the efficacy, safety, and tolerability of sodium nitroprusside (SNP) in pediatric subjects. Objectives were to determine the persistence of the effect of SNP on blood pressure during stable infusion regimens lasting at least 12 hours and to assess the potential for rebound hypertension during a 30 minute blinded phase following administration of SNP for at least 12 hours when infusion is temporarily discontinued |
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| Item Description: | "Clinical study report.". - Proprietary information in this document has been redacted |
| Physical Description: | 1 PDF file (2, 92 pages) illustrations |