Wheat flour fortification and human health

Using varied study designs (none of which can confirm causality), investigators assessed the health impact of wheat flour fortification after it was implemented at large scale in countries. Folic acid was the most studied nutrient and the most studied outcomes were neural tube defects, cancer, folat...

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Bibliographic Details
Main Author: Pachón, Helena
Format: eBook
Language:English
Published: Cambridge Burleigh Dodds Science Publishing 2021
Series:Burleigh Dodds Series in Agricultural Science
Subjects:
Online Access:
Collection: Directory of Open Access Books - Collection details see MPG.ReNa
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653 |a thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TV Agriculture and farming::TVK Agronomy and crop production 
653 |a thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TV Agriculture and farming::TVF Sustainable agriculture 
653 |a effectiveness 
653 |a Agronomy and crop production / bicssc 
653 |a nutrients 
653 |a thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TV Agriculture and farming::TVB Agricultural science 
653 |a Sustainable agriculture / bicssc 
653 |a wheat flour 
653 |a Agricultural science / bicssc 
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520 |a Using varied study designs (none of which can confirm causality), investigators assessed the health impact of wheat flour fortification after it was implemented at large scale in countries. Folic acid was the most studied nutrient and the most studied outcomes were neural tube defects, cancer, folate status, folate deficiency, anemia, iron deficiency, iron status, hemoglobin and iron-deficiency anemia (IDA). For all of these outcomes except IDA, the majority of studies showed improvements after fortification. For some of the outcomes (cancer, anemia, hemoglobin, folate deficiency), there were studies that indicated health outcomes worsened after fortification. The discrepant results for cancer may be due to years since fortification initiated and sample size differences. The preponderance of the evidence suggests that wheat flour fortification improves many health outcomes. Because fortification may also be associated with negative health outcomes such as cancer, health monitoring should continue to assess these outcomes in countries with fortification.