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Marine Compounds and Cancer 2020

The very first marine-derived anticancer drug, Cytarabine (aka Ara-C, Cytosar-U®), was approved by the FDA in 1969 for the treatment of leukemia. At the beginning of 2021, the list of approved marine-derived anticancer drugs consists of nine substances, five of which received approval within the las...

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Bibliographic Details
Main Author:	Honecker, Friedemann
Other Authors:	Dyshlovoy, Sergey A.
Format:	eBook
Language:	English
Published:	Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
Subjects:	Antioxidant Lampetra Morii Multidrug Resistance Bromophenol Apoptosis-inducing Activity Cell Adhesion Molecules Abc Transporter P38α Brevianamide Nur77 Humulane Sesquiterpenoids Ad0157 P38/erk Nf-κb Signaling Plakortide Marine-derived Drugs Fucoidan Tumor Microenvironment Trabectedin Non-small Cell Lung Carcinoma Fau Antiproliferative Activity Membrane Permeabilization Fucoxanthin Angiogenesis Inhibitor Tumor Cell Line Mitochondria Kalkitoxin Sponges Epithelial–mesenchymal Transition Pel Antitumour Human Sarcoma Cell Line (ht1080 Cells) Pi3k/akt Cytoskeleton Penicillium Brevicompactum Endoperoxide Non-small Cell Lung Cancer Marine Antitumor Agents Cembranoids Polyoxygenated Steroids Sipholenol A Jaspine B Anthranilic Acid Prostate Cancer Sz-685c Fbdd A375 And Hela Cell Lines Synergism Bel-7402 Cell Gliotoxin Natural Marine Compounds Hydroxylated Lipids Brominated Indoles Nf-κb Seaweed Phycocyanin Arrest Of Cell Cycle Cancer Anticarcinogenic Epigonal Organ Caspase Cascade Lung Cancer Antiangiogenic Programmed Cell Death-ligand 2 Cancer Genes Lyngbya Majuscula Mrp1/abcc1 Xyloketal B Antiangiogenesis Penicillium Paneum Cyclin D1 Et-743 Chromatography Chemotherapy Anti-metastatic Activity Sediment Invasion Novel Inhibitor Cytotoxicity Proteomic Proliferation Pyrrolidinedione Tgf-β Signaling Nsclc Circulating Tumor Cells Moorea Producens Bioactive Natural Product Antiproliferative Hif-1 Cytotoxic Activity Microalgae Mitochondria Toxin Ansamycins Marine Natural Products Cystatin F Porifera C-jun N/a Gemcitabine λ-carrageenan Natural Products Anti-cancer 3-alkylpyridinium Polymers 12-deacetyl-12-epi-scalaradial Fascaplysin Cell Adhesion Inhibitor Autophagy Inhibitors Neuroblastoma-rat Sarcoma Ros Energy Stress Antifouling Glioblastoma Molecular Docking Streptomyces Sp. Scsio 11594 Cell Cycle Arrest Poly(adp-ribose)-polymerase Inhibitor Benzo[a]pyrene Pachastrissamine Carotenoid Stat3 Ap-1 Topoisomerase Chemoprevention Pheochromocytoma And Paraganglioma Mechanisms Of Action Polysaccharides Selenium-containing Polysaccharide-protein Complex Cyp1a1 Dna Minor Groove Binder αo-conotoxin Gexiva Snora62 Chemosensitization C-met Marine Sponges Anticancer Immunity β1-integrin Emt Topo I Inhibitor Drug Discovery Leukemia Marine Drug Antibacterial Phlorotannins P38 Antitumor Activities Puupehenones Cancer Progression Fumigaclavine C Fatty Acid 2-hydroxylase Manzamine A Chop Gene Expression Marine Organisms Breast Cancer Cells Sea Anemone Anti-proliferation Heparanase Marine Mollusc Leathesia Nana Soft Tissue Sarcoma Divergolides P65 Cantabrian Sea-derived Actinobacteria Itampolin A Soft Coral Ecklonia Cava Programmed Cell Death Hypoxia Marthasterias Glacialis L. Hepatocellular Carcinoma Cancer Preventive Autophagy Inducers Mitochondrial Pathway Kunitz Type Inhibitor Glycosaminoglycans Safety Non-small Cell Lung Cancer (nsclc) Marine Metabolites Tnfα Dibromotyrosine Carotenoids Cyclin-dependent Kinase Cisplatin Nicotinic Acetylcholine Receptor Sepia Ink Polysaccharides Pollution Mapk/erk Pathway Her2 Small Cell Lung Cancer Mcp-1 Haliclona Gracilis Anti-angiogenic Thalassiolin B Clinical Trials Bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane (bddpm) Isofistularin Gorgonian Antitumor Molecular Oncology Human Lung Cancer Elisidepsin P2x7 Receptor Akt Rgd Motif Lung Metastasis Uveal Melanoma Secondary Metabolites Bioanalysis Azoxymethane Reactive Oxygen Species Colorectal Cancer Nanoparticle Chemical Conjugation Naphthopyrones Human Normal Diploid Fibroblast (tig-1 Cells) Sphingosine Kinase Inhibitor Trpm7 Depolymerisation Multi-drug Resistant Leukemia Heparan Sulphate Therapeutic Compounds Carcinoembryonic Antigen Anti-proliferative Antibody Drug Conjugates (adcs) Araguspongine C Triterpene Glycosides Melanoma Integrin β1 Ls-1 Low Molecular Weight Fucoidan Extract Molecular Mechanisms Autophagy Migration Anticancer Agent Mycalin A Micromonospora Evolution Molecular Modeling Tilapia Piscidin 4 (tp4) Hela Cells Sea Cucumbers Natural Product Targeted Therapy Aspergillus Bcrp/abcg2 Cytokine Release C15 Acetogenins Polyphenols Fak Mitochondrial Dysfunction Sinulariolide Anti-angiogenesis Pazopanib Terpenes Marangucyclines Thalassia Testudinum α9-nicotinic Acetylcholine Receptors (nachrs) Angiogenesis Cell Cycle Dieckol Inflammation Sarcophyton Ehrenbergi Vegf Tetracenomycin X Actinomycin Chimera Glucocorticoid Receptor Synthetic Analogues Fatty Acids Carbocyclic Analogue Hsp90 Medicine / Bicssc Mycochromenic Acid Derivative Deep-sea Cell Migration N-ras Nicotine Preclinical Hypoxia-inducible Factor-1 Anticoagulation Jurkat Shrimp Pseudopterosin A549 Cells Caribbean Sponge Anticancer Jnk1/2 Antitumoral Mangrove-derived Actinomycete Marine Fungus Anticoagulant Ribosomal Protein Genes Macrolide Marine Biotechnology Anticancer Activity Apoptosis Approved Antitumor Agents Hippuristanol Nonfunctioning Pituitary Adenomas Breast Cancer Proteasomal Degradation Camptothecin Sponge Endophytic Fungus Virtual Screening Palmitic Acid Aeroplysinin Cystatin Superfamily Rps30 Porifera/sponge Snorna Paulomycins Cooperative Binding Metastasis Ulva Fasciata Programmed Cell Death-ligand 1 Tumor-associated Macrophages Lipid Rafts Marine Drugs Oxidative Stress Il-6 Antimicrobial Peptide (amp) Low Toxic Isatin Leptogorgia Bonnethead Shark Osteosarcoma Endothelial Cells Hybridization P-gp/abcb1 Er-stress In Vivo Model Snu-c5/5-fu Phase I Signal Transduction Plitidepsin Adriamycin Resistance Marine Compound Chemopreventive Buccal Gland
Online Access:	https://www.mdpi.com/books/book/3853 https://directory.doabooks.org/handle/20.500.12854...
Collection:	Directory of Open Access Books - Collection details see MPG.ReNa

Description
Summary:	The very first marine-derived anticancer drug, Cytarabine (aka Ara-C, Cytosar-U®), was approved by the FDA in 1969 for the treatment of leukemia. At the beginning of 2021, the list of approved marine-derived anticancer drugs consists of nine substances, five of which received approval within the last two years, demonstrating the rapid evolution of the field. The current book is a collection of scientific articles related to the exponentially growing field of anticancer marine compounds. These articles cover the whole field, from agents with cancer-preventive activity, to novel and previously characterized compounds with anticancer activity, both in vitro and in vivo, as well as the latest status of compounds under clinical development.
Item Description:	Creative Commons (cc), https://creativecommons.org/licenses/by/4.0/
Physical Description:	1 electronic resource (480 p.)
ISBN:	9783036506319 books978-3-0365-0631-9 9783036506302

Marine Compounds and Cancer 2020

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