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210907 r ||| eng |
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|a Shekelle, Paul G.
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|a Efficacy and comparative effectiveness of off-label use of atypical antipsychotics
|h Elektronische Ressource
|c prepared for Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services ; prepared by Southern California/RAND Evidence-based Practice Center ; investigators, Paul Shekelle ... [et al.]
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|a Rockville, MD
|b Agency for Healthcare Research and Quality
|c 2007, [2007]
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|a Includes bibliographical references
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|a Antipsychotic Agents / adverse effects
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|a Off-Label Use
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|a Antipsychotic Agents / therapeutic use
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|a Southern California Evidence-Based Practice Center/RAND.
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|a United States
|b Agency for Healthcare Research and Quality
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|a eng
|2 ISO 639-2
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|b NCBI
|a National Center for Biotechnology Information
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|a Comparative effectiveness review
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|a Title from PDF title page (viewed on July 25, 2011). - "January 2007.". - "Contract No. 290-02-0003."
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|u https://www.ncbi.nlm.nih.gov/books/NBK43235
|3 Volltext
|n NLM Bookshelf Books
|3 Volltext
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|a 610
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|a Aripiprazole, olanzapine, quetiapine, risperidone, and ziprasidone are atypical antipsychotics approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia and bipolar disorder. These drugs have been studied for off-label use in the following conditions: dementia and severe geriatric agitation, depression, obsessive-compulsive disorder, posttraumatic stress disorder, and personality disorders. The atypicals have also been studied for the management of Tourette's syndrome and autism in children. The purpose of this report is to review the scientific evidence on the safety and effectiveness of such off-label uses
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