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210512 ||| eng |
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|a 9783039212040
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|a 9783039212033
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|a books978-3-03921-204-0
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|a Szostak, Michal
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245 |
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|a Amide Bond Activation
|h Elektronische Ressource
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|b MDPI - Multidisciplinary Digital Publishing Institute
|c 2019
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300 |
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|a 1 electronic resource (466 p.)
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|a formylation
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|a C-N ? bond cleavage
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|a cytostatic activity
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|a twisted amide
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|a pre-catalysts
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|a C-N bond cleavage
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|a nitrogen heterocycles
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|a rotational barrier energy
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|a DMF
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|a carbanions
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|a Winkler-Dunitz parameters
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|a fumardiamide
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|a additivity principle
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|a amides
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|a reaction mechanism
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|a density functional theory
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|a amide bond activation
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|a molecular dynamics
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|a [2+2+2] annulation
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|a bridged lactams
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|a amino acid transporters
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|a intein
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|a succindiamide
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|a N-dimethylacetamide
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|a amination
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|a heterocycles
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|a trialkylborane
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|a twisted amides
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|a C-H functionalization
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|a aminosulfonylation
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|a Suzuki-Miyaura
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|a antibacterial screening
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|a multi-component coupling reaction
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|a acyl transfer
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|a amidicity
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|a homogeneous catalysis
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|a ester bond activation
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|a palladium
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|a base-catalyed hydrolysis
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|a pharmacokinetics
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|a intramolecular catalysis
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|a pancreatic cancer cells
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|a Michael acceptor
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|a sodium
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|a physical organic chemistry
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|a DMAc
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|a cyclization
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|a aminoacylation
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|a distortion
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|a non planar amide
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|a tert-butyl
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|a enzymes
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|a dipeptides
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|a directing groups
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|a N-heterocyclic carbene
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|a transamidation
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|a C-H/C-N activation
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|a rhodium
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|a N
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|a amide bonds
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|a metal complexes
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|a catalysis
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|a metabolic stability
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|a aryl esters
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|a amide bond resonance
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|a pyramidal amides
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|a N-C activation
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|a C-H acidity
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|a HERON reaction
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|a Pd-catalysis
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|a steric effects
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|a acylative cross-coupling
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|a amide
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|a crown ether
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|a amine
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|a kinetic
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|a in situ
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|a nitro-aci tautomerism
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|a C-H bond cleavage
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|a water solvation
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|a protease
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|a biofilm eradication
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|a density-functional theory
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|a addition reaction
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|a amide bond
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|a thiourea
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|a secondary amides
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|a nickel catalysis
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|a C-O activation
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|a nuclear magnetic resonance
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|a excited state
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|a organic synthesis
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|a amidation
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|a N-heterocyclic carbenes (NHCs)
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|a ruthenium (Ru)
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|a C-S formation
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|a model compound
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|a amide resonance
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|a amide hydrolysis
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|a bridged sultams
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|a arynes
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|a catalyst
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|a N-dimethylformamide
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|a carbonylation
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|a cis/trans isomerization
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|a cyclopentadienyl complexes
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|a aryl thioamides
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|a cyanation
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|a insertion
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|a transition metals
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|a transition-metal-free
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|a synthesis
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|a amide activation
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|a thioamidation
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|a entropy
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|a amide C-N bond activation
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|a anomeric effect
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|a reaction thermodynamics
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|a hypersensitivity
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|a primaquine
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|a DFT study
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|a activation
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|a carbonylicity
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|a cross-coupling
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|a N-(1-naphthyl)acetamide
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|a palladium catalysis
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|a sulfonamide bond
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|a gemcitabine prodrug
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|a alkynes
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|a peptide bond cleavage
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|a Chemistry / bicssc
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|a antiviral activity
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|a catalysts
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|a eng
|2 ISO 639-2
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|b DOAB
|a Directory of Open Access Books
|
500 |
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|a Creative Commons (cc), https://creativecommons.org/licenses/by-nc-nd/4.0/
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|a 10.3390/books978-3-03921-204-0
|
856 |
4 |
2 |
|u https://directory.doabooks.org/handle/20.500.12854/40763
|z DOAB: description of the publication
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|u https://www.mdpi.com/books/pdfview/book/1420
|7 0
|x Verlag
|3 Volltext
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|a 540
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|a 333
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|a 380
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|a The amide bond represents a privileged motif in chemistry. The recent years have witnessed an explosion of interest in the development of new chemical transformations of amides. These developments cover an impressive range of catalytic N-C bond activation in electrophilic, Lewis acid, radical, and nucleophilic reaction pathways, among other transformations. Equally relevant are structural and theoretical studies that provide the basis for chemoselective manipulation of amidic resonance. This monograph on amide bonds offers a broad survey of recent advances in activation of amides and addresses various approaches in the field.
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