Digital Twins Applications to the Design and Optimization of Bioprocesses

This is the second of two volumes that together provide an overview of the latest advances in the generation and application of digital twins in bioprocess design and optimization. Both processes have undergone significant changes over the past few decades, moving from data-driven approaches into th...

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Bibliographic Details
Other Authors: Herwig, Christoph (Editor), Pörtner, Ralf (Editor), Möller, Johannes (Editor)
Format: eBook
Language:English
Published: Cham Springer International Publishing 2021, 2021
Edition:1st ed. 2021
Series:Advances in Biochemical Engineering/Biotechnology
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Potential of model-based design of experiments approaches for bioprocess scale-down
  • Digital Twins and Their Role in Model-Assisted Design of Experiments
  • Digital twins for bioprocess control strategy development and realization
  • The Kalman filter for the supervision of cultivation processes.-The challenge of implementing digital twins in operating value chains
  • Digital twins in the (bio)pharma industry
  • Numerical methods for the design and description of in vitro expansion processes of human mesenchymal stem cells
  • Euler-Lagrangian Simulations: A Proper Tool for Predicting Cellular Performance in Industrial Scale Bioreactors