Sugammadex for the reversal of rocuronium-induced neuromuscular blockade in surgical patients a review of clinical effectiveness

In patients undergoing surgery requiring general anesthesia, a neuromuscular blocking agent is often used to paralyze the vocal cords and facilitate intubation of the trachea and improve surgical conditions. At the conclusion of surgery, the NMB must be reversed, and depending on the depth of the NM...

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Bibliographic Details
Main Authors: Brett, Kendra, Farrah, Kelly (Author)
Corporate Author: Canadian Agency for Drugs and Technologies in Health
Format: eBook
Language:English
Published: Ottawa (ON) Canadian Agency for Drugs and Technologies in Health August 21, 2019, 2019
Series:CADTH rapid response report: summary with critical appraisal
Subjects:
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
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245 0 0 |a Sugammadex for the reversal of rocuronium-induced neuromuscular blockade in surgical patients  |h Elektronische Ressource  |b a review of clinical effectiveness  |c Kendra Brett, Kelly Farrah 
246 3 1 |a Summary with critical appraisal sugammadex for the reversal of neuromuscular blockade in surgical patients 
260 |a Ottawa (ON)  |b Canadian Agency for Drugs and Technologies in Health  |c August 21, 2019, 2019 
300 |a 1 PDF file (39 pages)  |b illustrations 
505 0 |a Includes bibliographical references 
653 |a Sugammadex 
653 |a Anesthesia Recovery Period 
653 |a Treatment Outcome 
653 |a Rocuronium / antagonists & inhibitors 
700 1 |a Farrah, Kelly  |e [author] 
710 2 |a Canadian Agency for Drugs and Technologies in Health 
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520 |a In patients undergoing surgery requiring general anesthesia, a neuromuscular blocking agent is often used to paralyze the vocal cords and facilitate intubation of the trachea and improve surgical conditions. At the conclusion of surgery, the NMB must be reversed, and depending on the depth of the NMB, the recovery may be spontaneous or a reversal agent can be administered. The purpose of this report is to synthesize and critically appraise the available evidence on the clinical effectiveness of sugammadex for rocuronium-induced NMB in patients undergoing surgery. This information may be used to inform decision making relating to health policy of the use of sugammadex