Detection of and adjustment for selection bias in randomized controlled clinical trials
| Main Author: | |
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| Format: | eBook |
| Language: | English |
| Published: |
London
Henry Stewart Talks
2020, 2020
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| Series: | Design and analysis of randomized clinical trials : design, analysis & theory
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| Subjects: | |
| Online Access: | |
| Collection: | Henry Stewart Talks - Collection details see MPG.ReNa |
Table of Contents:
- Introduction to selection bias
- Accrual character of clinical trials
- Restricted randomization procedures
- Blinding, masking of past treatment assignments
- Impact of 3rd order selection bias on clinical trial results
- Mathematical model to detect and adjust for 3rd order selection bias
- Restricted random walk
- Maximum likelihood estimators and their properties
- Consistency and asymptotic normality
- Likelihood ratio test