Study on the Cellular Regulation and Function of Lysine Malonylation, Glutarylation and Crotonylation

This book presents pioneering findings on the characterization of cellular regulation and function for three recently identified protein posttranslational modifications (PTMs): lysine malonylation (Kmal), glutarylation (Kglu) and crotonylation (Kcr). It addresses three main topics: (i) Detecting Kma...

Full description

Main Author: Bao, Xiucong
Corporate Author: SpringerLink (Online service)
Format: eBook
Published: Singapore Springer Singapore 2020, 2020
Edition:1st ed. 2020
Series:Springer Theses, Recognizing Outstanding Ph.D. Research
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Introduction to Protein Posttranslational Modifications (PTMs)
  • Chemical reporter for Lysine Malonylation
  • Identification of Histone Lysine Glutarylation
  • Glutarylation at Histone H4 lysine 91 Modulates Chromatin Assembly
  • Identification of Sirt3 as an ‘Eraser’ for Histone Lysine Crotonylation Marks using a Chemical Proteomics Approach