Structure–Activity Relationships for Development of Neurokinin-3 Receptor Antagonists Reducing Environmental Impact
This book explores the possible development of neurokinin-3 receptor (NK3R) antagonists with reduced environmental impact. Pharmaceuticals are used to cure diseases and to alleviate symptoms in humans and animals. However, the stable, bioactive substances excreted by patients have unfavorable effect...
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| Format: | eBook |
| Language: | English |
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Singapore
Springer Nature Singapore
2020, 2020
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| Edition: | 1st ed. 2020 |
| Series: | Springer Theses, Recognizing Outstanding Ph.D. Research
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| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- 1. Introduction
- 2. Development of NK3R Antagonists with a Labile Functional Group in the Natural Environment
- 3. Development of NK3R Antagonists with a Degradable Scaffold in the Natural Environment: Synthesis and Application of Fused Piperazine Derivatives for Investigation of Degradable Core Motifs
- 4. Development of NK3R Antagonists with a Degradable Scaffold in the Natural Environment: Identification of NK3R Antagonists with a Decomposable Core Structure by Scaffold Hopping
- 5. Conclusion