The Biology of mRNA: Structure and Function

The book provides an overview on the different aspects of gene regulation from an mRNA centric viewpoint, including how mRNA is assembled and self-assembles in a complex consisting of RNA and proteins, and how its ability to be translated at the right time and space depends on many processes acting...

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Bibliographic Details
Other Authors: Oeffinger, Marlene (Editor), Zenklusen, Daniel (Editor)
Format: eBook
Language:English
Published: Cham Springer International Publishing 2019, 2019
Edition:1st ed. 2019
Series:Advances in Experimental Medicine and Biology
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Regulation of co-transcriptional mRNP assembly
  • mRNA export through the NPC
  • Roles of mRNA modifications in gene regulation
  • Studying mRNPs using single molecule approaches
  • Difference between mRNPs and lncRNAs?
  • RNPs and/or sequence motives in mRNA localization
  • mRNP structure
  • New RNA binding proteins: mRNP composition
  • Aggregation of repeats RNAs in neurodegenerative diseases
  • mRNA structural organization and translation
  • How to decide to make an mRNA - degradation
  • Methods to study mRNP composition
  • mRNA-DNA kisses – R-loops
  • Forms of mRNA editing and their role in disease