Modeling of antibody-drug conjugate pharmacokinetics
| Main Author: | |
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| Format: | eBook |
| Language: | English |
| Published: |
London
Henry Stewart Talks
2019, 2019
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| Series: | Periodic reports : advances in clinical interventions and research platforms
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| Subjects: | |
| Online Access: | |
| Collection: | Henry Stewart Talks - Collection details see MPG.ReNa |
Table of Contents:
- Antibody drug conjugates (ADCs) and their uses
- Different ways to measure ADCs in the cell
- Typical ADC PK in cells
- Modeling the cellular PK of ADCs
- Modeling the tumor PK of ADCs
- 7 steps
- Modeling whole-body PK of ADCs
- Combining PK and PD models
- Kadcyla case study