Computational Methods for Single-Cell Data Analysis

This detailed book provides state-of-art computational approaches to further explore the exciting opportunities presented by single-cell technologies. Chapters each detail a computational toolbox aimed to overcome a specific challenge in single-cell analysis, such as data normalization, rare cell-ty...

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Bibliographic Details
Other Authors: Yuan, Guo-Cheng (Editor)
Format: eBook
Language:English
Published: New York, NY Humana 2019, 2019
Edition:1st ed. 2019
Series:Methods in Molecular Biology
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Quality Control of Single-cell RNA-seq
  • Normalization for Single-cell RNA-seq Data Analysis
  • Analysis of Technical and Biological Variability in Single-cell RNA Sequencing
  • Identification of Cell Types from Single-cell Transcriptomic Data
  • Rare Cell Type Detection
  • scMCA- A Tool Defines Cell Types in Mouse Based on Single-cell Digital Expression
  • Differential Pathway Analysis
  • Differential Pathway Analysis
  • Estimating Differentiation Potency of Single Cells using Single Cell Entropy (SCENT)
  • Inference of Gene Co-expression Networks from Single-Cell RNA-sequencing Data
  • Single-cell Allele-specific Gene Expression Analysis
  • Using BRIE to Detect and Analyse Splicing Isoforms in scRNA-seq Data
  • Preprocessing and Computational Analysis of Single-cell Epigenomic Datasets
  • Experimental and Computational Approaches for Single-cell Enhancer Perturbation Assay
  • Antigen Receptor Sequence Reconstruction and Clonality Inference from scRNA-seq Data
  • A Hidden Markov Random Field Modelfor Detecting Domain Organizations from Spatial Transcriptomic Data