| Summary: | The inadequacy of traditional cleaning methods has been linked to operator errors in relation to improper selection, formulation, distribution, and contact time of the disinfectant. Approaches to improve cleaning effectiveness include educational campaigns, feedback of cleaning performance, routine microbiological analysis of surface hygiene, and the use of fluorescent markers or assays to assess the thoroughness of cleaning. While these measures can improve conventional cleaning efficiency, their sustainability has not been studied. The use of non-manual room disinfection reduces the chances of operator errors associated with traditional cleaning methods and offers the potential for more effective eradication of pathogens to reduce transmission of infections. In this report, non-manual refers to non-touch or automated procedures, or environmentally active agents. A previous Rapid Response report found low quality evidence for the effectiveness of VHP and an UV room disinfection system to prevent or reduce infection rates in a healthcare setting. The aim of this review is to review the available evidence for the clinical and cost-effectiveness of non-manual room disinfection techniques for the prevention of infections in healthcare facilities
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