| Summary: | Oral cancers can develop in any part of the mouth, but most oral cancers start within the tongue or the floor of the mouth. They can also spread or originate from the bony structures of the mandibles. Oral cancers are commonly treated with ablative surgery alone or in combination with radiation and/or chemotherapy. Ablative surgeries may range from minor soft tissue trimming to a major resection of the tongue and jaw and face bones. Ablative surgeries of the face and mouth can introduce significant defects in the orofacial region. If not restored, these defects can compromise essential functions such as mastication, speech, and even breathing. Therefore, prosthetic rehabilitation is planned along with the ablative surgery. Oral prosthetics are usually constructed for edentulous patients, and they are stabilized and retained over the jaw bones. However, their stability and retention can be compromised due to the ablative surgery conducted on oral soft tissues and bone. The use of osseointegrated implants is suggested to improve the stability and retention of oral prosthetics in oral cancer patients. Osseointegrated implants are metallic, or even ceramic, structures which can be fixed within the jaw bones. They are connected to external structures which can be used to anchor oral prostheses. Classically, oral prostheses are put directly on the defective area and rely on the remaining oral structure for retention and stability. The purpose of this report is to review the evidence of the clinical effectiveness and cost-effectiveness of immediate osseointegrated implants for cancer patients
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