Central venous access devices (CVADs) and peripherally inserted central catheters (PICCs) for adult and pediatric patients a review of clinical effectiveness and safety

Central venous access devices (CVADs) or central venous catheters (CVCs) are devices that are inserted into the body through a vein to enable the administration of fluids, blood products, medication and other therapies to the bloodstream. CVADs can be inserted into the subclavian or jugular vein (im...

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Bibliographic Details
Main Authors: Ho, Chuong, Spry, Carolyn (Author)
Corporate Author: Canadian Agency for Drugs and Technologies in Health
Format: eBook
Language:English
Published: Ottawa (ON) Canadian Agency for Drugs and Technologies in Health April 27, 2017, 2017
Series:Rapid response report: summary with critical appraisal
Subjects:
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
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245 0 0 |a Central venous access devices (CVADs) and peripherally inserted central catheters (PICCs) for adult and pediatric patients  |h Elektronische Ressource  |b a review of clinical effectiveness and safety  |c Chuong Ho, Carolyn Spry 
260 |a Ottawa (ON)  |b Canadian Agency for Drugs and Technologies in Health  |c April 27, 2017, 2017 
300 |a 1 PDF file (13 pages)  |b illustrations 
505 0 |a Includes bibliographical references 
653 |a Comparative Effectiveness Research 
653 |a Central Venous Catheters / statistics & numerical data 
653 |a Catheterization, Peripheral / statistics & numerical data 
653 |a Treatment Outcome 
653 |a Risk Assessment 
700 1 |a Spry, Carolyn  |e [author] 
710 2 |a Canadian Agency for Drugs and Technologies in Health 
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520 |a Central venous access devices (CVADs) or central venous catheters (CVCs) are devices that are inserted into the body through a vein to enable the administration of fluids, blood products, medication and other therapies to the bloodstream. CVADs can be inserted into the subclavian or jugular vein (implanted ports, tunneled catheters), or can be inserted into one of the peripheral veins of the upper extremities, called peripherally inserted central catheters (PICCs).1 While generally safe, CVADs can be associated with complications such as catheter occlusion or rupture, venous thrombosis, and bloodstream infection.1 A number of strategies have been used to minimize the occurrence of CVAD- and PICC-associated complications such as antimicrobial-impregnated lines for prevention of infection, or addition of a valve (valved catheters) to prevent occlusion by preventing reflux of blood into the catheter.2 Flushing the catheters with saline or heparin - an agent with anticoagulant activity - have been used to reduce clot formation and occlusion of the catheters. This Rapid Response report is an update of the previous CADTH reports which found no difference in terms of frequency of occlusion in patients who had a valved versus a non-valved PICCs, and similar patency between heparin and saline use for CVCs.3,4 This report aims to review the evidence on the clinical effectiveness of valved versus non-valved PICCs, and saline versus heparin flushing in the maintenance of CVADs patency and reduction of complications