A Metaheuristic Approach to Protein Structure Prediction Algorithms and Insights from Fitness Landscape Analysis

This book introduces characteristic features of the protein structure prediction (PSP) problem. It focuses on systematic selection and improvement of the most appropriate metaheuristic algorithm to solve the problem based on a fitness landscape analysis, rather than on the nature of the problem, whi...

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Bibliographic Details
Main Authors: Jana, Nanda Dulal, Das, Swagatam (Author), Sil, Jaya (Author)
Format: eBook
Language:English
Published: Cham Springer International Publishing 2018, 2018
Edition:1st ed. 2018
Series:Emergence, Complexity and Computation
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
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245 0 0 |a A Metaheuristic Approach to Protein Structure Prediction  |h Elektronische Ressource  |b Algorithms and Insights from Fitness Landscape Analysis  |c by Nanda Dulal Jana, Swagatam Das, Jaya Sil 
250 |a 1st ed. 2018 
260 |a Cham  |b Springer International Publishing  |c 2018, 2018 
300 |a XXIX, 220 p. 59 illus., 54 illus. in color  |b online resource 
505 0 |a Metaheuristic Protein Structure Prediction-An Overview -- Related Works -- Continuous Landscape Analysis using Random Walk Algorithm -- Landscape Characterization and Algorithms Selection for the PSP Problem -- The Levy distributed Parameter Adaptive Metaheuristic Algorithm for Protein Structure Prediction -- Protein Structure Prediction using Improved Variants of Metaheuristic Algorithms -- Hybrid Metaheuristic Approach for Protein Structure Prediction -- Conclusions and Future Research 
653 |a Proteins 
653 |a Computational intelligence 
653 |a Applied Dynamical Systems 
653 |a Artificial Intelligence 
653 |a Computational Intelligence 
653 |a Nonlinear theories 
653 |a Artificial intelligence 
653 |a Dynamics 
700 1 |a Das, Swagatam  |e [author] 
700 1 |a Sil, Jaya  |e [author] 
041 0 7 |a eng  |2 ISO 639-2 
989 |b Springer  |a Springer eBooks 2005- 
490 0 |a Emergence, Complexity and Computation 
028 5 0 |a 10.1007/978-3-319-74775-0 
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520 |a This book introduces characteristic features of the protein structure prediction (PSP) problem. It focuses on systematic selection and improvement of the most appropriate metaheuristic algorithm to solve the problem based on a fitness landscape analysis, rather than on the nature of the problem, which was the focus of methodologies in the past. Protein structure prediction is concerned with the question of how to determine the three-dimensional structure of a protein from its primary sequence. Recently a number of successful metaheuristic algorithms have been developed to determine the native structure, which plays an important role in medicine, drug design, and disease prediction. This interdisciplinary book consolidates the concepts most relevant to protein structure prediction (PSP) through global non-convex optimization. It is intended for graduate students from fields such as computer science, engineering, bioinformatics and as a reference for researchers and practitioners