Precision Medicine, CRISPR, and Genome Engineering Moving from Association to Biology and Therapeutics

This book presents descriptive overviews of gene editing strategies across multiple species while also offering in-depth insight on complex cases of application in the field of tissue engineering and regenerative medicine.  Chapters feature contributions from leaders in stem cell therapy and biology...

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Bibliographic Details
Other Authors: Tsang, Stephen H. (Editor)
Format: eBook
Language:English
Published: Cham Springer International Publishing 2017, 2017
Edition:1st ed. 2017
Series:Advances in Experimental Medicine and Biology
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Part 1. Introduction to the CRISPR Revolution.- 1. Viral Vectors, Engineered Cells and the CRISPR Revolution
  • 2.  Combining Engineered Nucleases with Adeno-associated Viral Vectors for Therapeutic Gene Editing
  • Part 2. CRISPR in Model Systems
  •  3. From Reductionism to Holism: Toward a More Complete View of Development through Genome Engineering
  • 4. Genome Engineering in Mice
  • 5. Genome Editing to Study Ca2+ Homeostasis in Zebrafish Cone Photoreceptors
  • 6. From Prokaryotic Immune Systems to Plant Genome Editing Tools
  • 7. Part 3. The Future of CRISPR
  • 7. Using High-throughput Gene Editing to Identify Therapeutic Targets in the Noncoding Genome
  • 8. CRISPR in the Retina: Evaluation of Future Potential
  • 9. The Future of CRISPR Applications in the Lab, the Clinic and Society