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D-type Cyclins and Cancer

This volume provides an integrated account of our current understanding of the functions of D-type cyclins during development and tumorigenesis, with special emphasis on the kinase-independent functions of these proteins. The volume will provide a thorough review of the latest discoveries on the new...

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Bibliographic Details
Other Authors: Hinds, Philip W. (Editor), Brown, Nelson E. (Editor)
Format: eBook
Language:English
Published: Cham Humana 2018, 2018
Edition:1st ed. 2018
Series:Current Cancer Research
Subjects:
Medicine / Research
Biology / Research
Cytological Techniques
Cancer
Biomedical Research
Cytology / Technique
Cancer Biology
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • The D-type Cyclins: A Historical Perspective
  • Mammalian Development and Cancer – A Brief History of Mice Lacking D-type Cyclins or Cdk4/6
  • D-type Cyclins and Gene Transcription
  • Splice Variants and Phosphorylated Isoforms of Cyclin D1 in Tumorigenesis
  • Cyclin D1, Metabolism, and the Autophagy-Senescence Balance
  • Shifting a Paradigm: Cyclin D Activates pRb by Mono-Phosphorylation

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