Scleroderma From Pathogenesis to Comprehensive Management
Comprised of the authoritative work of international experts, this fully-updated second edition of Scleroderma builds upon the well-regarded approach in the first edition to provide integrated, concise, and up-to-date synthesis of current concepts of pathogenesis and modern approaches to management...
| Other Authors: | , , , |
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| Format: | eBook |
| Language: | English |
| Published: |
Cham
Springer International Publishing
2017, 2017
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| Edition: | 2nd ed. 2017 |
| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Section IV. Cardiovascular Manifestations and Management
- Raynaud’s Phenomenon, Digital Ulcers, and Nailfold Capillaroscopy
- Renal Crisis and Other Renal Manifestations of Scleroderma
- Cardiac Involvement
- Section V. Pulmonary Manifestations and Management
- Overview of Lung Involvement: Diagnosis, Differential Diagnosis, and Monitoring
- Clinical Assessment of Lung Disease
- Treatment of Interstitial Lung Disease
- Pathogenesis of Pulmonary Arterial Hypertension
- Clinical Assessment of Pulmonary Hypertension
- The Management of Pulmonary Arterial Hypertension in the Setting of Systemic Sclerosis
- Section VI. Gastrointestinal Manifestations and Management
- Overview of Gastrointestinal Tract Involvement
- Upper Gastrointestinal Tract: Manifestations of Systemic Sclerosis
- Small and Large Intestinal Involvement and Nutritional Issues
- Section VII. Skin, Musculoskeletal and Other Complications
- Calcinosis
- Evaluation and Management of Skin Disease
- Section I. Introduction
- Historical Perspective of Scleroderma
- Section II. Epidemiology, Genetics and Classification
- Epidemiology, Environmental and Infectious Risk Factors
- Genetic Factors
- Disease Subsets in Clinical Practice
- Evolving Concepts of Diagnosis and Classification
- Overlap Syndromes
- Juvenile Localized and Systemic Scleroderma
- Morphea (Localized Scleroderma)
- Scleroderma Mimics
- Systems Biology Approaches to Understanding the Pathogenesis of Systemic Sclerosis
- Section III: The Biological Basis of Systemic Sclerosis
- Introduction: The Etiopathogenesis of Systemic Sclerosis: An Integrated Overview
- Pathology of Systemic Sclerosis
- Inflammation and Immunity
- Autoantibodies as Markers and Possible Mediators of Scleroderma Pathogenesis
- The Clinical Aspects of Autoantibodies
- Mechanisms of Vascular Disease
- Biomarkers in Systemic Sclerosis
- Pathophysiology of Fibrosis in Systemic Sclerosis
- Overview of Animal Models
- Managing the Ischemic Finger in Scleroderma
- Scleroderma Renal Crisis
- Rapid Diffuse Skin Disease with Progressive Joint Contractures
- Management of the Scleroderma Patient with Pulmonary Arterial Hypertension Failing Initial Therapy
- Pseudo-obstruction with Malabsorption and Malnutrition
- Progressive Interstitial Lung Disease Non-Response to Cyclophosphamide
- Coping with the Disfigurement of Scleroderma: Facial, Skin, and Hand Changes
- Managing Complicated Digital Ulcers
- Assessment and Management of Progressive Skin Involvement in Diffuse Scleroderma
- Skeletal Muscle Involvement
- Tendons, Joints, and Bone
- Cancer in Systemic Sclerosis
- Overlooked Manifestations
- Pregnancy
- Section VIII: Management and Outcome Assessment
- Introduction to Section VIII: Management and Outcome Assessment
- Immunomodulatory, Immunoablative, and Biologic Therapies
- Investigative Approaches to Drug Therapy
- Drug Development and Regulatory Considerations for SSc Therapies
- Physical and Occupational Therapy
- Psychosocial Issues and Care for Patients with Systemic Sclerosis
- Clinical Trial Design in Systemic Sclerosis
- Measuring Disease Activity and Outcomes in Clinical Trials
- Innovative Approaches to Clinical Trials in Systemic Sclerosis
- Molecular Stratification by Gene Expression as a Paradigm for Precision Medicine in Systemic Sclerosis
- Section IX. Case Studies: Approach to Complex Clinical Problems