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160406 ||| eng |
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|a 9784431560159
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| 100 |
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|a Yamasaki, Sho
|e [editor]
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| 245 |
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|a C-Type Lectin Receptors in Immunity
|h Elektronische Ressource
|c edited by Sho Yamasaki
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| 250 |
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|a 1st ed. 2016
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| 260 |
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|a Tokyo
|b Springer Japan
|c 2016, 2016
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| 300 |
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|a VI, 215 p. 29 illus., 6 illus. in color
|b online resource
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| 505 |
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|a Part 1 ITAM-coupled Activating Receptors -- 1 Dectin-2 in anti-microbial immunity and homeostasis -- 2 The function of Mincle as a danger sensor -- 3 The DAP12-Associated Myeloid C-type Lectin 5A (CLEC5A) -- Part 2 HemITAM-bearing Receptors -- 4 Dectin-1 (CLEC7A, BGR, CLECSF12) -- 5 DNGR-1, an F-actin-binding C-type lectin receptor involved in cross-presentation of dead cell-associated antigens by dendritic cells -- 6 C-type lectin-like receptor 2 (CLEC-2) -- Part 3 ITIM-bearing Receptors -- 7 Dendritic cell immunoreceptor (DCIR): An ITIM-harboring C-type lectin receptor -- 8 Regulation and Function of the Inhibitory C-type Lectin Clec12A/MICL -- Part 4 Other receptors and related topics -- 9 DC-SIGN in infection and immunity -- 10 LOX-1 and immunity -- 11 MGL/CD301 as a unique C-type lectin expressed on dendritic cells and macrophages -- 12 Structural aspects of C-type lectin receptors -- 13 The Ligands of C-Type Lectins
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| 653 |
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|a Pharmaceutical chemistry
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| 653 |
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|a Immunology
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| 653 |
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|a Pharmaceutics
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| 653 |
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|a Biochemistry
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| 041 |
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7 |
|a eng
|2 ISO 639-2
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| 989 |
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|b Springer
|a Springer eBooks 2005-
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| 028 |
5 |
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|a 10.1007/978-4-431-56015-9
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| 856 |
4 |
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|u https://doi.org/10.1007/978-4-431-56015-9?nosfx=y
|x Verlag
|3 Volltext
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| 082 |
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|a 616.079
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| 082 |
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|a 571.96
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| 520 |
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|a The book presents the latest findings on C-type lectin receptors, focusing on individual receptors and their signaling. In recent years there have been great advances in the understanding of the function of these receptors as a newly emerging family of pattern-recognition receptors (PRRs) for pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs). Comprising four parts: ITAM-coupled Activating Receptors; HemITAM-bearing Receptors; ITIM-bearing Receptors; and Other Receptors and Related Topics, this comprehensive review covers a broad range of C-type lectin receptors. The updated information on C-type lectin receptors and their ligands provided will appeal to a wide readership, from basic immunologists to physicians and surgeons. In addition, sections on novel drug development make this a valuable resource for pharmaceutical scientists
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