Sertoli Cell Metabolism and Spermatogenesis

This book is focused on Sertoli cell physiology and its role in the spermatogenic event. These cells, known as “nurse cells”, are essential for the normal development of germ cells by offering not only physical support and creating an immune-privileged environment, but also for providing nutritional...

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Main Authors: Oliveira, Pedro F., Alves, Marco G. (Author)
Corporate Author: SpringerLink (Online service)
Format: eBook
Language:English
Published: Cham Springer International Publishing 2015, 2015
Edition:1st ed. 2015
Series:SpringerBriefs in Cell Biology
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
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245 0 0 |a Sertoli Cell Metabolism and Spermatogenesis  |h Elektronische Ressource  |c by Pedro F. Oliveira, Marco G. Alves 
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505 0 |a 1 Introductory remarks -- 2 The Sertoli cell at a glance -- 3 Spermatogenesis -- 4 Sertoli cell and germ cell differentiation -- 5 Testicular Metabolic Cooperation -- 6 Modulation of Sertoli cell metabolism -- 7 Concluding remarks -- 8 Acknowledgments -- 9 References 
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700 1 |a Alves, Marco G.  |e [author] 
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520 |a This book is focused on Sertoli cell physiology and its role in the spermatogenic event. These cells, known as “nurse cells”, are essential for the normal development of germ cells by offering not only physical support and creating an immune-privileged environment, but also for providing nutritional support. The presence of Sertoli cells promotes the establishment of the appropriate microenvironment so that spermatogenesis may occur. Spermatogenesis maintenance in vivo is highly dependent on the metabolic cooperation established between Sertoli cells and developing germ cells. For many years this metabolic cooperation between testicular cells has been disregarded, but recent advances have highlighted the relevance of these processes for male fertility. Thus, the understanding of the functioning and regulation of these metabolic processes is a crucial step to identify key mechanisms associated with Sertoli cell (dys)function and to enlighten their influence on male fertility