Physical Biology of Proteins and Peptides Theory, Experiment, and Simulation

This book covers the latest developments in the physical biology of proteins and peptides. Key insights into microscopic and macroscopic approaches to describe biologically relevant macromolecules and their interactions are provided. This book also covers a wide range of tools, including theoretical...

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Bibliographic Details
Other Authors: Olivares-Quiroz, Luis (Editor), Guzmán-López, Orlando (Editor), Jardón-Valadez, Hector Eduardo (Editor)
Format: eBook
Language:English
Published: Cham Springer International Publishing 2015, 2015
Edition:1st ed. 2015
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
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100 1 |a Olivares-Quiroz, Luis  |e [editor] 
245 0 0 |a Physical Biology of Proteins and Peptides  |h Elektronische Ressource  |b Theory, Experiment, and Simulation  |c edited by Luis Olivares-Quiroz, Orlando Guzmán-López, Hector Eduardo Jardón-Valadez 
250 |a 1st ed. 2015 
260 |a Cham  |b Springer International Publishing  |c 2015, 2015 
300 |a XI, 177 p  |b online resource 
505 0 |a Chapter 1 The structural determinants of the immunoglobulin light chain amyloid aggregation -- Chapter 2 Thermodynamics and kinetics of amyloid aggregation from atomistic simulations -- Chapter 3 Determination of the size of the primary and secondary folding nuclei of protofibrils from the concentration dependence of the rate and the lag-time of their formation -- Chapter 4 Modulation of cholera toxin structure/function by Hsp90 -- Chapter 5 Function, structure and stability of human gamma D crystallins: A review -- Chapter 6 Protein motions, dynamic effects and thermal stability in dihydrofolate reductase from the hyperthermophile Thermotoga maritime -- Chapter 7 Ab initio folding of glycophorin A and acetylcholine M2 transmembrane segments via simplified environment molecular simulations -- Chapter 8 Multi-scale approaches to dynamical transmission of protein allostery -- Chapter 9 Dynamics of membrane proteins and lipid bilayers -- Chapter 10 What makes a transcriptional master regulator?A systems biology approach 
653 |a Bioinformatics 
653 |a Biophysics 
653 |a Protein Biochemistry 
653 |a Computational and Systems Biology 
653 |a Proteins  
653 |a Proteins 
700 1 |a Guzmán-López, Orlando  |e [editor] 
700 1 |a Jardón-Valadez, Hector Eduardo  |e [editor] 
041 0 7 |a eng  |2 ISO 639-2 
989 |b Springer  |a Springer eBooks 2005- 
028 5 0 |a 10.1007/978-3-319-21687-4 
856 4 0 |u https://doi.org/10.1007/978-3-319-21687-4?nosfx=y  |x Verlag  |3 Volltext 
082 0 |a 572.6 
520 |a This book covers the latest developments in the physical biology of proteins and peptides. Key insights into microscopic and macroscopic approaches to describe biologically relevant macromolecules and their interactions are provided. This book also covers a wide range of tools, including theoretical methods as statistical mechanics, normal mode analysis, kinetic theory and stochastic processes, and all-atom and coarse-grained molecular dynamics simulations. New experimental techniques are also discussed, particularly related to amiloidogenic peptides and their mutations. This is an excellent book for molecular biologists, physicists, computational scientists, and chemists. It covers cutting-edge research in this exciting, interdisciplinary research field. This book also: Discusses the latest developments in the physical biology of proteins, peptides and enzymes covering theoretical, computational, and experimental approaches B roadens readers’ understanding on the role of intra- and inter-molecular interactions as a fundamental cornerstone of macroscopic biological properties of macromolecules Provides a wide and useful perspective on different aspects of the physics, biology, and chemistry of proteins and peptides suitable for interdisciplinary research