Cell cycle control by the ubiquitin system in mammals
| Main Author: | |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
London
Henry Stewart Talks
2009, 2009
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| Series: | The cell division cycle : controlling when and where cells divide and differentiate
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| Subjects: | |
| Online Access: | |
| Collection: | Henry Stewart Talks - Collection details see MPG.ReNa |
Table of Contents:
- Ubiquitin-proteasome system
- What regulates the cell division cycle?
- Cyclin dependent kinases
- Advantages of regulated proteolysis
- The hierarchy of the ubiquitin pathway
- E2s and E3s ensure substrate specificity
- Regulation of the cell cycle by proteolysis
- Two major ubiquitin ligases control cell cycle progression
- SCF ubiquitin ligases
- Mechanism of catalysis by the SCF
- F-box proteins
- Skp2
- betaTrcp1 and betaTrcp2
- DNA replication stress
- Fbxw7
- Anaphase promoting complex or cyclosome
- Cell cycle, ubiquitin system and cancer