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02538nmm a2200277 u 4500 |
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EB001083334 |
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EBX01000000000000000842741 |
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20240125000000.0 |
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151019 ||| eng |
| 100 |
1 |
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|a Flockhart, David A.
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| 245 |
0 |
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|a Germline pharmacogenomics as a tool to individualize therapy in breast cancer
|h Elektronische Ressource
|c David A. Flockhart
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| 260 |
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|a London
|b Henry Stewart Talks
|c 2009, 2009
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| 300 |
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|a 1 online resource (1 streaming video file (43 min.)
|b color, sound)
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| 505 |
0 |
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|a Major clinical issues in the personalized treatment of breast cancer -- The efficacy barrier: tamoxifen and anastrozole -- Advances in targeting that have improved the treatment of breast cancer -- Tumor-based expression arrays -- Prognostic expression arrays remain valuable beyond tumor grade and stage -- Pharmacogenetic principles -- Principles for valuable predictive biomarkers -- COBRA -- Anti-estrogen therapy for breast cancer -- The ELPH trial -- Aromatase inhibitor side effects in the ELPH trial -- The problem with aromatase inhibitors in Asia -- Breast cancer around the world -- Classic understanding of tamoxifen pharmacology -- Tamoxifen metabolism -- Endoxifen -- Serum concentrations of tamoxifen and metabolites predict efficacy -- CYP2D6 -- Relapse-free survival was worse in poor metabolizers -- Clinical consequences -- Pharmacodynamic pharmacogenomics -- Multiple targets to inhibit angiogenesis -- Bevacizumab in breast cancer
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| 653 |
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|a Neoplasms / therapy
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| 653 |
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|a Breast Neoplasms / genetics
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| 653 |
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|a Neoplasms / complications
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| 653 |
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|a Breast Neoplasms / drug therapy
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| 041 |
0 |
7 |
|a eng
|2 ISO 639-2
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| 989 |
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|b HST
|a Henry Stewart Talks
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| 490 |
0 |
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|a Cancer therapy : latest thinking in efficacy and toxicity
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| 500 |
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|a Animated audio-visual presentation with synchronized narration. - Title from title frames. - Mode of access: World Wide Web. - System requirements: Browser compatibility: updated Mozilla Firefox, Google Chrome, Safari or Internet Explorer 8+. Browser settings: enable JavaScript, enable cookies from the Henry Stewart Talks site. Required Desktop Browser plugins & viewers: Updated Adobe Flash Player & Adobe Acrobat Reader. Mobile device & operating system versions: Android v4.0+, iPhone 4+ (iOS v6.x+), iPad 2+ (iOS v6.x+), BlackBerry OS v7.0+, Windows Phone v6.5.1+
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| 856 |
4 |
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|u https://hstalks.com/bs/1124
|x Verlag
|z Streaming video file
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| 856 |
4 |
2 |
|u https://hstalks.com/bs/p/385
|3 Series
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| 082 |
0 |
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|a 570
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