Possible roles of mitochondrial biogenesis in aging
| Main Author: | |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
London
Henry Stewart Talks
2007, 2007
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| Series: | Mitochondrial biogenesis : processes, regulation, functions and disease
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| Subjects: | |
| Online Access: | |
| Collection: | Henry Stewart Talks - Collection details see MPG.ReNa |
Table of Contents:
- Oxidative phosphorylation
- The mitochondrial DNA
- Aging as the accumulation of damage
- Types of aging damage
- Types of damaged cells
- Survival of cells lacking oxidative phosphorylation
- The plasma membrane redox system
- Reductive hotspot hypothesis
- "Survival of the slowest" hypothesis
- Allotopic expression
- Hydrophobicity prevents allotopic expression of mitochondrially-encoded proteins
- Ways to make these proteins allotopically expressible