Checkpoint blockade in cancer immunotherapy
| Main Author: | |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
London
Henry Stewart Talks
2007, 2007
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| Series: | Monoclonal antibodies as therapeutic agents : fundamentals, therapeutic applications and latest advances
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| Subjects: | |
| Online Access: | |
| Collection: | Henry Stewart Talks - Collection details see MPG.ReNa |
Table of Contents:
- Activation of naive T-cells
- CD28 and CTLA-4
- Differential regulation of T-cell responses
- Responding repertoire
- Biological role of CTLA-4
- Tumor-specific immune responses
- Treg activity
- CTLA-4/GVax
- Immunotherapies
- Conventional therapies
- Ipilumumab
- Clinical studies: melanoma
- Reversible immune mediated toxicity