MPG.eBooks - Table of Contents: Protein networks and analysis of global gene expression

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Bibliographic Details
Main Author:	Ideker, Trey
Format:	eBook
Language:	English
Published:	London Henry Stewart Talks 2007, 2007
Series:	From DNA to proteins : the multiple levels of regulation
Subjects:	Computational Biology Genomics / Methods Bioinformatics Models, Genetic Systems Biology Genetic Regulatory Networks Proteins / Metabolism Protein Protein Interactions Saccharomyces Cerevisiae / Genetics Fungal Proteins / Metabolism Gene Expression Regulation, Fungal / Physiology Gene Expression Regulation / Physiology Databases, Protein Proteomics Proteomics / Methods Gene Regulatory Networks / Physiology Systems Biology / Trends Protein Interaction Maps / Genetics Computational Biology / Trends
Online Access:	https://hstalks.com/bs/639 https://hstalks.com/bs/p/22
Collection:	Henry Stewart Talks - Collection details see MPG.ReNa

Table of Contents:

A paradigm shift: from databases of protein sequences to protein interactions
Technologies for measuring interactions
Chromatin immunoprecipitation (ChIP)
Yeast Two Hybrid (Y2H) technology
Mass spectrometry based approaches
Methods for querying protein networks with gene expression profiles
Systematic validation of protein network models using gene deletions
Cytoscape open-source software for network modeling and visualization
Methods for network comparison across species
Application to discover conserved protein complexes among the networks of yeast, worm, fly and Plasmodium
Methods for querying protein networks to explain genetic (synthetic lethal) interactions
Future directions: how network queries will enable systems biology